Archive for the ‘METH - METHLABS’ Category

CYANIDE ANTIDOTE – FDA APPROVED RECENTLY – WILL IMPROVE FIRE AND POISONED VICTIMS’ CHANCES OF SURVIVAL WITH EARLY EMS AND KEY TO BIOTERRORISM MONITORING *** CYANOKIT (C)

Monday, January 15th, 2007

Fire victims, EMS providers, methlab remediation teams, and firefighters will be greatly served by this medical advancement in the United States.  This cyanide antidote replaces the "lilly kit" that had been used for years, which used early, was lifesaving but medically cumbersome at best.  Three medicines quickly had to be given to these severely critical patients – and the antidote itself had poisoning problems itself.  This new antidote uses an extremely novel idea.  Vitamin B12, hydroxycobalamin, likes cyanide.  With a little molecular twist, the new antidote drug, hydroxocobalamin, simply exchanges a part of the drug and binds the cyanide with impressive results.  Dr. Steve Borron, well know to some of us, and definitely an international leader in this arena, has done significant and life changing research on this new antidote to get the approval through the FDA.  This antidote has been used in Europe for over a decade with great success.  Others like Dr. Hall in Denver has done work on the FDA project years ago.  Many have contributed to this landmark success of getting this drug in a workable form into the United States.  Congrats to all of them!

 

FDA News

FOR IMMEDIATE RELEASE
P06-205
December 15, 2006

Media Inquiries:
Press Office, 301-827-6242
Consumer Inquiries:
888-INFO-FDA

FDA Approves Drug to Treat Cyanide Poisoning

The Food and Drug Administration (FDA) today approved Cyanokit (containing the drug hydroxocobalamin, intravenous tubing and a sterile spike for reconstituting the drug product with saline) for the treatment of known or suspected cyanide poisoning.  The approval, which is based on evidence of the drug's effectiveness when tested in animals, improves the nation's ability to respond to emergencies, including a potential attack by terrorists.

"Cyanide is a potent poison and one of the substances that could be used in a chemical attack," said Dr. Steven Galson, Director of FDA's Center for Drug Evaluation and Research.  "Today's approval is yet another measure to counter the threat of terrorism, which is a critical component of FDA's public health mission."

Cyanokit received a priority review and was approved under the Animal Efficacy Rule, which  allows use of animal data for evidence of a drug's effectiveness for certain conditions when the drug cannot be ethically or feasibly tested in humans. 

In a controlled study in cyanide-poisoned adult dogs, the use of Cyanokit reduced whole blood cyanide concentration by approximately 55% by the end of the infusion, and significantly improved survival of the Cyanokit-treated dogs compared with dogs receiving placebo.

The safety, metabolism and excretion of Cyanokit were evaluated in 136 healthy adult humans.  At the proposed starting dose of 5 grams, the drug was found to be generally well tolerated with side effects that were mild to moderate.  The drug exits the body unchanged in the urine.  In the presence of cyanide, Cyanokit's active drug takes up the cyanide and becomes a form of vitamin B12.

The most frequently reported adverse reactions in the trial were red urine, skin redness (both from the drug's coloration itself), a temporary increase in blood pressure, headache, nausea and injection site reactions.  Allergic reactions were observed in a small number of individuals but were relatively mild and responded quickly to treatment.

Cyanokit is manufactured for EMD Pharmaceuticals, Inc by Merck Sante s.a.s. in Semoy, France and packaged by Dey Laboratories of Napa, California.

More information about FDA's efforts to counteract bioterrorism is available on FDA's website at http://www.fda.gov/oc/opacom/hottopics/bioterrorism.html.

 

(photos courtesy: google images)

 

METH LABS — smurfing — AFTER THE CLEANUP IS RISK REAL? TOXIC TALE?

Friday, January 12th, 2007

Methlabs continue to plague society. Costs continue to rise.  New laws embedded.  New techniques on how to get the drugs to help make meth continue, for example:

Typical mechanisms that the non-cartel methlab cooks get pseudoephedrine are: smurfing and shelf sweeping.  Individuals that “smurf” go to a large number of stores and buy amounts at each retailer of pseudoephedrine that are under the legal limit but in the aggregate are much more.  A less sophisticated version of smurfing involves sending many individuals into the same store to buy amounts of pseudoephedrine just below the legal limit.  “Shelf sweeping” occurs when an individual or a group goes into a store and remove all the pseudoephedrine on the shelf and then exit without paying.

 

 

photo courtesy srhd

 

 

Recently, radio listening to a report of the "significant" risks to persons entering into methlab areas that already have been cleaned up or decontaminated or remediated.  The report left me believing that any site with any amount of meth activity is the same.  Not true.

The report said after the cleanup process has occurred, the persons are still able to be "poisoned" and become "toxic" from being in the decontaminated room.  Not probable either.

The epidemic of methlabs across the country have spawned the entire "cleanup industry" making many companies extremely wealthy in the "abatement industry."  One operator told me, "If I just turn on the truck, the fee is $2500 dollars, then the bill goes up depending on what we do."

Most ingredients of methlabs are dangerous.  Some can be flammable.  Some have bombs or incindary devices. However, after the cleanup has occurred, risk is minimal, probably non-existent.

Do you clean out your garage or shed as a methlab decon project – the spaces that have been storage for such contaminants of lawn mower gasoline, oil, garden chemicals, camping or cooking supplies, glass cleaner, carburator fluids, drain cleaners, windshield washer fluids, antifreeze, and other highly toxic day to day chemicals of household use?

The risk of financial collapse for cleanup is hard hitting for any owner that needs to hire a "cleanup" company.  It is estimated that a methlab cleanup can cost from $1000 to hundreds of thousands, depending on cartel activity or the mom-pop variety.

Google "methlab cleanup companies" (remediation) and nearly 60,000 hits arrive at the "deal or no deal" option.

Searching and searching, little is found on "risk of after-cleanup toxicity."   Colleagues in this area have been surveyed.  An anwer is in waiting.  Thus far, experience has not shown me one person ill, sick, contaminated, physically harmed, toxic from a space declared "clean."

 

CARBON MONOXIDE (CO) POISONING EPIDEMIC * prevention – WARNING – CAUSES – SYMPTOMS – THERAPY – GOAL – LONG TERM EFFECTS – **mandatory reporting effort by Washington State Public Health and Washington Posion Center

Friday, December 22nd, 2006

 

 

Preventing Carbon Monoxide Poisoning   *  Emergency

 

(fires photos from:  nifc.gov)
(product photos from:  web general sites)
(house photo from: kltv, texas)

 

Generators, grills, camp stoves, or other gasoline, propane, natural gas, or charcoal-burning devices should never be used inside a home, basement, garage, or camper – or even outside near an open window. 

Every home should have at least one working carbon monoxide detector. The detector’s batteries should be checked twice annually, at the same time smoke detector batteries are checked.

Carbon monoxide (CO) is an odorless, colorless gas that can cause sudden illness and death if inhaled.
When power outages occur during emergencies such as hurricanes or winter storms, the use of alternative sources of fuel or electricity for heating, cooling, or cooking can cause CO to build up in a home, garage, or camper and to poison the people and animals inside.

Every year, more than 500 people die in the U. S. from accidental CO poisoning.
CO is found in combustion fumes, such as those produced by small gasoline engines, stoves, generators, lanterns, and gas ranges, or by burning charcoal and wood. CO from these sources can build up in enclosed or partially enclosed spaces. People and animals in these spaces can be poisoned and can die from breathing CO.

How to Recognize CO Poisoning
Exposure to CO can cause loss of consciousness and death. The most common symptoms of CO poisoning are headache, dizziness, weakness, nausea, vomiting, chest pain, and confusion. People who are sleeping or who have been drinking alcohol can die from CO poisoning before ever having symptoms.

Important CO Poisoning Prevention Tips

  • Never use a gas range or oven to heat a home.
  • Never use a charcoal grill, hibachi, lantern, or portable camping stove inside a home, tent, or camper.
  • Never run a generator, pressure washer, or any gasoline-powered engine inside a basement, garage, or other enclosed structure, even if the doors or windows are open, unless the equipment is professionally installed and vented. Keep vents and flues free of debris, especially if winds are high. Flying debris can block ventilation lines.
  • Never run a motor vehicle, generator, pressure washer, or any gasoline-powered engine outside an open window, door, or vent where exhaust can vent into an enclosed area.
  • Never leave the motor running in a vehicle parked in an enclosed or partially enclosed space, such as a garage.
  • If conditions are too hot or too cold, seek shelter with friends or at a community shelter.
  • If CO poisoning is suspected, consult a health care professional right away.

 

Educational materials

 

(adapted from CDC website)

 

Indications for Hyperbaric Oxygen

Hyperbaric oxygen therapy is a specialized medical treatment in which the patient breathes 100 per cent oxygen while inside a chamber at increased atmospheric pressure. HBO is used for specific medical conditions. HBO has long been (PHOTO: hcmc hbo ctr) recognized as vital in the resolution of critical medical conditions such as gas gangrene, carbon monoxide poisoning, air embolism due to diving, trauma, or surgical procedures, and decompression sickness. It is also an important adjunct for specific wound healing conditions.

 

The Hyperbaric Oxygen Committee of the Undersea and Hyperbaric Medical Society (UHMS) lists the following indications: approved uses for Hyperbaric Oxygen therapy:

  • Air or gas embolism
  • Carbon monoxide poisoning and smoke inhalation
  • Clostridial myonecrosis (gas gangrene)
  • Crush injury, compartment syndrome, and other acute traumatic ischemias
  • Decompression sickness
  • Enhancement of selected problem wounds
  • Exceptional blood loss anemia
  • Necrotizing soft tissue infections
  • Chronic refractory osteomyelitis
  • Radiation tissue damage (Osteoradionecrosis)
  • Skin grafts and flaps (compromised)
  • Thermal burns
  • Adjunctive HBO in intracranial abscess

 

 (adapted from:  HCMC HBO Ctr)

 

 

Carbon monoxide poisoning: Reporting required

Due to the ongoing severe cold weather conditions and associated increase in carbon monoxide (CO) poisoning among King County (PHOTO: hcmc hbo ctr)  residents, Public Health is making suspected CO poisoning immediately reportable to Public Health by hospitals and healthcare provi
ders for seven days from today, through Dec. 24, 2006
. This period will be extended if necessary.

The most common symptoms of CO poisoning are headache, dizziness, weakness, nausea, vomiting, chest pain, and confusion. Inhalation of carbon monoxide gas typically leads to headache, dizziness, and confusion, which might progress to dyspnea, tachypnea, syncope, and metabolic acidosis.  Laboratory criteria for diagnosis: A case in which carboxyhemoglobin concentration exists >5% in venous or arterial blood in nonsmokers and >10% in smokers, as determined by hospital or commercial laboratory tests. The typical range of carboxyhemoglobin concentrations in smokers is 6%-10%.

 

Advice regarding diagnosis and treatment management of CO intoxication is available 24/7 through Washington State Poison Center at 1-800-222-1222.

This health order impacts primarily emergency departments (ED) and the information should be disseminated to all ED staff in King County hospitals immediately. A designated person on each shift should be identified to report cases of CO poisoning to Public Health.

 (adapted from the Seattle/King County Public Health Announcement) 

THE CONTROVERSY CONTINUES:  DOES THE HYPERBARIC OXYGEN HELP?

Current assessment and treatment of CO poisoning in the
emergency department is grossly inadequate to prevent serious
neurologic complications. HBOT speeds removal of CO from
tissues and counters a number of its deleterious effects. Past studies
have demonstrated efficacy of HBOT for reducing the incidence of
neurologic sequelae, even though only three sessions of HBOT
were used. Clinical experience such as that reported here shows that
HBOTtreatment late in the course of established impairments from
CO can lead to clinical improvements. Improvement is documented
by evidence of increased brain metabolism on functional brain
imaging by SPECT after HBOT. Further study as well as wider
availability of HBOT, particularly for persons such as firefighters
who are at high occupational risk of CO poisoning, is warranted. 

AND THESE TREATMENTS ARE NOT CONCLUSIVE IN MANY STUDIES THUS FAR…(editorial comment by castMD.com)

Richard A. Neubauer, M.D.
Virginia Neubauer
Alan Ko Chi Nu,
M.D. William S.
Maxfield, M.D., FACNM
, is Medical Director, Ocean Hyperbaric
Neurologic Center, Lauderdale-by-the-Sea, FL. is
Research Director, Ocean Hyperbaric Neurologic Center.
, is a hyperbaric physician practicing in Taipei, Taiwan.
, is a radiologist and Chief of Nuclear Medicine at
Ocean Hyperbaric Neurologic Center.

(adapted from:  Journal of American Physicians and Surgeons Volume 11 Number 2 Summer 2006)

FIBER – SOLUBLE FIBER AND WEIGHT CONTROL ***DIETING WITHOUT PILLS, DRUGS OR METH *** HIGH VOLUME soluble FIBER SUPPLEMENTS happy healthy holidays

Tuesday, December 19th, 2006

Over the past 20 – 30 years, fiber has been a leading dietary factor connected to worsening weight control.  Less fiber, less control has been the health risk.  You should have noticed on "The Biggest Loser" tv show in 2006 that dietary fiber amounts were noticeable.  So this idea of weight control and dieting with its relationship to fiber intake is not a new idea.  The real concern with increasing obesity, diabetes, cancer, and childhood obesity and its complications, is the amount of fiber, and the type of fiber that is of special focus today.

Generally, obese men and women have less fiber in their diets.  In fact, overweight persons generally consume about one-half of the fiber that is recommended.  Many times, programs for weight loss find that the "client" is not using enough fiber to assist in weight loss management, therefore causing increased risk of failure of the weight loss program.

Many persons do not like high-fiber in general.  Why? Foods like beans, whole grains, fruits, and vegetables can cause bloating and gas; and they just do not like that feeling.  Many jokes of such problems exist, but what really happens is tolerance to fiber does occur…it gets better.

High-fiber diets help your body making contents inside the bowel bulkier with water holding properties.  It helps distend your stomach, small and large bowel – helping you feel fuller longer.  It also causes the feeling of hunger to go away.

Soluble fiber especially causes a viscous suspension.  (See previous castMD detail at the link http://www.castmd.com/?p=36 . These slurries delay stomach emptying and allows nutrient absorption.  Hunger pains are minimized.  In addition, some fats are held in the fiber, allowing yet the proteins and carbohydrates to be absorbed.  This slowing, and delaying, and changing the food load is called "spreading the nutrient load."  

Fiber helps change the hormones that control food metabolism.  Sugar in your system is more stable, and even; and the metabolism is more controlled with insulin avoiding the highs and lows of sugar and its rebound in the blood stream.

With this better and longer control of your glycemic load, energy is maintained on lesser calories.  There are fewer "hunger signals" to the appetitie centers, allowing more work with less calories.  You're not eating as much and you are using calories already "on board."

Many parents with CAD (coronary artery disease) have overweight children.  And those kids had more complications of health risks that other kids.  With the addition of high-fiber, better control of weight, cholesterol, blood sugar, and insulin release was maintained.  Risk of "metabolic syndrome" or "syndrome X" goes down with high-fiber supplementation.  With this, insulin resistance goes down; –  while hyperlipidemia, hypertension, hypercholesterolemia and type 1 and type 2 diabetes all have improvement. 

Obesity continues as diets are high in fats, high in added sugars, and low in soluble fibers.

At least 25 to 30 grams of soluble fiber is recommended daily, slowly added from about 5 grams per day over 2-3 months – to maintain a healthy weight.

IN SUMMARY:     Cool     ENJOY THE HOLIDAYS HEALTHIER *

SOLUBLE FIBER HELPS SLOW DOWN THE RATE THAT FOOD NUTRIENTS ARE ABSORBED

SOLUBLE FIBER HELPS YOU FEEL LESS HUNGRY

SOLUBLE FIBER HELPS REDUCE THE AMOUNT OF CALORIES YOU TAKE IN

SOLUBLE FIBER HELPS PROTECT YOU FROM THE RISKS OF SEVERAL SERIOUS DISEASES. 

 

(excerpts from:  Soluble Fiber – Saving Your Health, Saving Your Money.  Winter & Crane)

COCAINE “ENERGY DRINK” IS CAFFEINE BASED – ALOT ! OVERDOSE potential ?

Tuesday, December 5th, 2006

THE LASTEST CRAZE OF ENERGY DRINKS IS THIS PRODUCT BY REDUX BEVERAGES FROM LAS VEGAS.  IT IS NOT COCAINE.  IT IS CAFFEINE BASED.  EACH UNIT HAS ABOUT 280 MG OF CAFFEINE.  THE AVERAGE COFFEE CUP HAS ABOUT 80 MG.

THE QUESTION IS:  IS IT UNETHICAL ADVERTISING TO HIGHLIGHT AND ENTICE THE "ABUSE" OF OVERUSE, OVERDOSE, AND GETTING HIGH WITH SUCH PRODUCTS?

CAFFEINE OVERDOSE IS A SERIOUS MATTER.  MANY TIMES THE KIDS THAT RELY ON THE "HIGH" MAY ALSO BE ABUSING OTHER AGENTS OF TOXICITY.

SHOULD WE ADVERTISE THE "HIGH" OF SNIFFING PAINT, PAINT IS A LEGAL PRODUCT ?

SHOULD WE ADVERTISE THE "HIGH" OF HUFFING COMPUTER AIR, AIR IS A LEGAL PRODUCT?

SHOULD WE ADVERTISE THE "HIGH" OF ALCOHOL, ALCOHOL IS A LEGAL PRODUCT?

THE ANSWER IS THAT THIS PRODUCT AND OTHERS, I BELIEVE, HIGHLIGHT ABUSE AND OVERUSE. 

TELLING A PARENT THAT THEIR SON OR DAUGHTER HAS DIED IN THE ER OR WAS D.O.A. IS A REAL EXPERIENCE THAT SOME OF US HAVE HAD TO BARE…

THE ANSWER IS: YES, IT IS UNETHICAL ADVERTISING AND MARKETING.  THE COMPANIES SHOULD BE HELD RESPONSIBLE FOR THE "ENTICING" APPROACH.  

DEATH BY CAFFEINE IS NOT ANY MORE CALMING THAN DEATH BY OTHER OVERDOSE MEANS. PARENTS BEWARE.

 

(adapted:  aceommroupdt)

METH BODY PACKIN’ ELMO EXTREME – BUSTED IN COLORADO

Tuesday, November 28th, 2006

One of the best stories for the holiday season, is the recent bust of the California to Colorado methamphetamine bust.

It was reported by the DEA in Colorado, the drug ring was using the Sesame Street character "Elmo" for the meth "mule."

None other than "Tickle Me Elmo Extreme" was apprehended with the pre-street loot !

Just like meth, able to cause the toxic agitation, convulsions, repetitive movements – the Elmo Extreme character laughs, rolls, and hits the ground uncontrollably…or until it shuts off.

Unfortunately, the infamous "war on drugs" has not shut off the resources, money, or mules for meth, cocaine, crack, crank, weed, or other drugs of abuse – especially at the southern US border.  With the Afghanistan poppy crop at one of its highest production years, the disconnect of drug curtailment and drug support continues within our own government.  And that is a "mind stretch."

IMMEDIATE CARE urgent care CLINICS – WHY WAIT IN THE ER MINOR EMERGENCY WALK IN URGENT CARE INJURY ILLNESS – WORKER OCCUPATIONAL CARE – DRUG-FREE WORKPLACE TESTING – MRO REVIEW – SPORTS CARE – FAMILY CARE – URGENT CARE

Wednesday, November 22nd, 2006
  • OVER THE PAST DECADE AT LEAST 400 HUNDRED OR MORE EMERGENCY ROOMS HAVE CLOSED
  • GREATER 120 MILLION PEOPLE WERE TREATED IN ERS A FEW YEARS AGO – GROWING
  • GROWTH IS AN ALARMING 20-30% EVERY 5-10 YEARS
  • COMPLICATED PATIENTS CONTINUE TO GROW – AIDS, TB, CANCER, ADVANCED DIABETES, STROKE, HEART DISEASE COMPLICATIONS, TRAUMA, SHOOTINGS, DRUGS OF ABUSE
  • NEARLY 50 MILLION AMERICANS HAVE NO INSURANCE OR LIMITED ACCESS

click on link -  http://www.nimcc.com

WHAT TO DO:

BRING A LIST OF YOUR ALLERGIES, MEDICATIONS, PAST MEDICAL HISTORY, EKG IF YOU HAVE IT, AND NAMES AND PHONE NUMBERS OF SIGNIFICANT OTHERS, AND INSURANCE INFO IF IN DATE 

 

GO TO IMMEDIATE CARE IF UNSURE  – IF NOT SEVERELY ILL OR INJURED

IF YOU MUST GO TO THE ER, GO IN THE MORNING…LESS BUSY USUALLY

WHEN IN DOUBT –  IF ILLNESS OR INJURY IS SEVERE…CALL 911

TELL THE TRIAGE NURSE YOUR SYMPTOMS…ALL OF THEM

KNOW THE CREDENTIALS OF YOUR DOCTOR…EXPERIENCE

IS THE EMERGENCY PHYSICIAN RESIDENCY TRAINED IN EMERGENCY MEDICINE

IS THE EMERGENCY PHYSICIAN BOARD-CERTIFIED IN EMERGENCY MEDICINE

BRING AN ADVOCATE TO WATCH, LISTEN, AND ASK QUESTIONS – ESPECIALLY IF VERY ILL

MANY IMMEDIATE CARE CLINICS CAN TAKE CARE OF MANY ILLNESSES AND MINOR EMERGENCIES – CALL IF UNSURE

MANY IMMEDIATE CARE CLINICS CAN STABILIZE AND TRANSFER TO THE HOSPITAL

MANY IMMEDIATE CARE CLINICS HAVE BOARD CERTIFIED ER DOCS AND ER EXPERIENCED DOCS

KNIGHTLY POETRY

Saturday, November 18th, 2006

GOOD KNIGHT©

THERE ONCE WAS A COACH NAMED KNIGHT
ALWAYS COACHING HIS WAY TO FIGHT,
TRUTH A CHANCE
WITH VERBAL DANCE. 
 

WARNING OH WARNING
FACIAL SCOURNING,
PLAYERS LOOK
FORCE THAT SHOOK.

THE TEACHER, THE MENTOR,
THE COACH, THE  TORMENTOR,
LEADING WINNING EDGE
CRUSH SOUND  POUNDING SLEDGE. 
 

FOR MONEY GAINS
DISCORD REMAINS,
YOUR SONS OF ROUNDBALL
WATCH PUBLIC CALL 
 

TECHNICAL – AT LEAST A FOUL
PLAYER’S REACTION DISEMBOWEL,
FOR AGES OF THE TRUE KNIGHT
COURAGE, VALOR, HONORABLE FIGHT.  
 

BUT OF THIS KNIGHT
OPPORTUNE BRIGHT,
BUT DIMS WITH AGE
NOW MINIMAL SAGE… 

castmd.com